The average bus between Santa Martha Acatitla and Tlaxcala takes 2h 35m and the fastest bus takes 2h 10m. There is a bus service every few hours from Santa Martha Acatitla to Tlaxcala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Santa Martha Acatitla and Tlaxcala. The earliest departure is at 3:05 AM at night, and the last departure from Santa Martha Acatitla is at 10:35 PM which arrives into Tlaxcala at 12:55 AM. All services require a transfer at Terminal de Autobuses de Pasajeros de Oriente and take an average of 2h 35m. The schedules shown below are for the next available departures.

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Want to know about travelling from Santa Martha Acatitla to Tlaxcala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Martha Acatitla to Tlaxcala. However, there are services departing from Santa Martha Acatitla station and arriving at Tlaxcala station via Terminal de Autobuses de Pasajeros de Oriente. The journey, including transfers, takes approximately 2h 35m.
Santa Martha Acatitla to Tlaxcala bus services, operated by Volcanes, depart from Carcel de Mujeres station.
Santa Martha Acatitla to Tlaxcala bus services, operated by Volcanes, arrive at Tlaxcala station.
The distance between Santa Martha Acatitla and Tlaxcala is 84.9 km. The road distance is 126 km.
You can take a bus from Carcel de Mujeres to Tlaxcala via Terminal de Autobuses de Pasajeros de Oriente and México TAPO in around 2h 22m.