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Santa Monica to Irvine buses

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Trip Overview

The average bus between Santa Monica and Irvine takes 4h 4m and the fastest bus takes 3h 12m. The bus service runs several times per day from Santa Monica to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 4m
Duration
64 mi
Distance
$10
Average price
4 times a day
Frequency

Line 33 bus, bus, line 53 bus

best
  1. Take the bus from 2nd / Broadway to Patsaouras Transit Plazabus bus 33
  2. Take the bus from Los Angeles Union Station to Anaheim Regional Transportation Intermodal Centerbus bus
  3. Take the bus from Artic - Dock 4 to Main-Harvardbus bus 53
4h 25m
$8–12

Santa Monica to Irvine bus times

Buses run 4 times a day between Santa Monica and Irvine. The earliest departure is at 4:58 AM at night, and the last departure from Santa Monica is at 7:09 PM which arrives into Irvine at 10:50 PM. All services require a transfer at Los Angeles Union Station and take an average of 4h 4m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

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    Metro Los AngelesFlixbus USAOCTA3h 12m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA3h 41m • 2 changes

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    Metro Los AngelesFlixbus USAOCTA3h 41m • 2 changes

Departing Sunday, November 1, 2026

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    Arrives next day

    Metro Los AngelesFlixbus USAOCTA9h 37m • 2 changes

Departing Monday, November 2, 2026

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    Metro Los AngelesGreyhound USAOCTA3h 48m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 18m • 2 changes

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    Metro Los AngelesFlixbus USAOCTA3h 52m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 9m • 2 changes
  • Show more

Departing Tuesday, November 3, 2026

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    Metro Los AngelesGreyhound USAOCTA3h 48m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 18m • 2 changes

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    Metro Los AngelesFlixbus USAOCTA3h 52m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 9m • 2 changes
  • Show more

Departing Wednesday, November 4, 2026

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    Metro Los AngelesGreyhound USAOCTA3h 48m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 18m • 2 changes

  •  → 

    Metro Los AngelesFlixbus USAOCTA3h 52m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 9m • 2 changes
  • Show more

Departing Thursday, November 5, 2026

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    Metro Los AngelesGreyhound USAOCTA3h 48m • 2 changes

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    Metro Los AngelesGreyhound USAOCTA4h 18m • 2 changes

  •  → 

    Metro Los AngelesFlixbus USAOCTA3h 52m • 2 changes

  •  → 

    Metro Los AngelesGreyhound USAOCTA4h 9m • 2 changes
  • Show more

Departing Friday, November 6, 2026

  •  → 

    Metro Los AngelesGreyhound USAOCTA3h 48m • 2 changes

  •  → 

    Metro Los AngelesGreyhound USAOCTA4h 18m • 2 changes

  •  → 

    Metro Los AngelesFlixbus USAOCTA3h 52m • 2 changes

Frequently asked questions

Want to know about travelling from Santa Monica to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Monica to Irvine.ExpandLaunch map view
  • Distance: 64.1 mi
  • Duration: 4h 4m

What companies run services between Santa Monica, CA, USA and Irvine, CA, USA?

You can take a bus from 2nd / Broadway to Main-Harvard via Los Angeles Union Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 4h 25m.

Operators