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Santander to Florence buses

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Trip Overview

The bus between Santander and Florence takes 43h 10m. The bus runs, on average, 6 times per week from Santander to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 10m
Duration
1,711 km
Distance
€175
Average price
6 times a week
Frequency

Santander to Florence bus times

Buses run 6 times a week between Santander and Florence. The service departs Santander at 5:50 PM in the evening, which arrives into Florence at 14:00:00. All services require a transfer, and take on average 43h 10m. The schedules shown below are for the next available departures.

Departing Monday, October 26, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus43h 10m • 1 change

Departing Tuesday, October 27, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus43h 10m • 1 change

Departing Wednesday, October 28, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus43h 10m • 1 change

Departing Thursday, October 29, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus43h 10m • 1 change

Departing Friday, October 30, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus43h 10m • 1 change

Departing Saturday, October 31, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus43h 10m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Florence.ExpandLaunch map view
  • Distance: 1,710.7 km
  • Duration: 43h 10m

What companies run services between Santander, Spain and Florence, Italy?

You can take a bus from Estación de autobuses de Santander to Florence Villa Constanza Bus Station via Bordeaux in around 24h 15m.

Operators