Santander to Guadalajara Buses

Santander to Guadalajara buses

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Trip Overview

The average bus between Santander and Guadalajara takes 6h 41m and the fastest bus takes 6h 25m. The bus service runs several times per day from Santander to Guadalajara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 41m
Duration: 460 km
Distance: €47
Average price: 5 times a day
Frequency

Bus

best

Take the bus from Estación de autobuses de Santander to Madrid, Avenida de Américabus ALSA - San-Mad / ...
Take the bus from Madrid, Avenida de América to Guadalajarabus ALSA - Mad-Gua / ...

6h 35m

€39–61

Santander to Guadalajara bus times

Buses run 5 times a day between Santander and Guadalajara. The earliest departure is at 1:00 AM at night, and the last departure from Santander is at 5:30 PM which arrives into Guadalajara at 12:15 AM. All services require a transfer, and take on average 6h 41m. The schedules shown below are for the next available departures.

Departing Monday, October 26, 2026

8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:45 PM
6h 45m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
5:30 PM → 12:15 AM
Arrives next day
6h 45m • 1 change

Departing Tuesday, October 27, 2026

1:00 AM → 7:40 AM
6h 40m • 1 change
8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:45 PM
6h 45m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
Show more

Departing Wednesday, October 28, 2026

1:00 AM → 7:40 AM
6h 40m • 1 change
8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:45 PM
6h 45m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
Show more

Departing Thursday, October 29, 2026

1:00 AM → 7:40 AM
6h 40m • 1 change
8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:45 PM
6h 45m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
Show more

Departing Friday, October 30, 2026

1:00 AM → 7:40 AM
6h 40m • 1 change
8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:45 PM
6h 45m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
Show more

Departing Saturday, October 31, 2026

1:00 AM → 7:40 AM
6h 40m • 1 change
8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:55 PM
6h 55m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
Show more

Departing Sunday, November 1, 2026

1:00 AM → 7:40 AM
6h 40m • 1 change
8:00 AM → 2:45 PM
6h 45m • 1 change
12:00 PM → 6:55 PM
6h 55m • 1 change
3:30 PM → 9:55 PM
6h 25m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Santander to Guadalajara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Santander to Guadalajara buses

Find Transport to Guadalajara

Trip Overview

Bus

Santander to Guadalajara bus times

Departing Monday, October 26, 2026

8:00 AM → 2:45 PM

12:00 PM → 6:45 PM

3:30 PM → 9:55 PM

5:30 PM → 12:15 AMArrives next day

Departing Tuesday, October 27, 2026

1:00 AM → 7:40 AM

8:00 AM → 2:45 PM

12:00 PM → 6:45 PM

3:30 PM → 9:55 PM

Departing Wednesday, October 28, 2026

1:00 AM → 7:40 AM

8:00 AM → 2:45 PM

12:00 PM → 6:45 PM

3:30 PM → 9:55 PM

Departing Thursday, October 29, 2026

1:00 AM → 7:40 AM

8:00 AM → 2:45 PM

12:00 PM → 6:45 PM

3:30 PM → 9:55 PM

Departing Friday, October 30, 2026

1:00 AM → 7:40 AM

8:00 AM → 2:45 PM

12:00 PM → 6:45 PM

3:30 PM → 9:55 PM

Departing Saturday, October 31, 2026

1:00 AM → 7:40 AM

8:00 AM → 2:45 PM

12:00 PM → 6:55 PM

3:30 PM → 9:55 PM

Departing Sunday, November 1, 2026

1:00 AM → 7:40 AM

8:00 AM → 2:45 PM

12:00 PM → 6:55 PM

3:30 PM → 9:55 PM

Frequently asked questions

What companies run services between Santander, Spain and Guadalajara, Spain?

Bus from Estación de autobuses de Santander to Madrid, Avenida de América

Bus from Madrid, Avenida de América to Guadalajara

Bus trips from Santander

Bus trips to Guadalajara

Alternative transport options

5:30 PM → 12:15 AM
Arrives next day