The average bus between Santander and Madrid Airport (MAD) takes 6h 25m and the fastest bus takes 5h 52m. The bus service runs several times per day from Santander to Madrid Airport (MAD). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Santander and Madrid Airport (MAD). The earliest departure is at 1:00 AM at night, and the last departure from Santander is at 5:30 PM which arrives into Madrid Airport (MAD) at 11:44 PM. All services require a transfer, and take on average 6h 25m. The schedules shown below are for the next available departures.

6h 29m • 1 change

6h 28m • 1 change

5h 52m • 1 change

6h 14m • 1 change

6h 8m • 1 change

6h 29m • 1 change

6h 28m • 1 change

5h 52m • 1 change

6h 8m • 1 change

6h 29m • 1 change

6h 28m • 1 change

5h 52m • 1 change

6h 8m • 1 change

6h 29m • 1 change

6h 28m • 1 change

5h 52m • 1 change

5h 57m • 1 change

6h 21m • 1 change

6h 25m • 1 change

5h 55m • 1 change

6h 8m • 1 change

6h 29m • 1 change

6h 28m • 1 change

5h 52m • 1 change
Want to know about travelling from Santander to Madrid Airport (MAD)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santander to Madrid Airport (MAD). However, there are services departing from Santander station and arriving at Madrid Airport (MAD) station via Madrid, Avenida de América. The journey, including transfers, takes approximately 6h 25m.
Santander to Madrid Airport (MAD) bus services, operated by ALSA, depart from Estación de autobuses de Santander station.
Santander to Madrid Airport (MAD) bus services, operated by ALSA, arrive at Madrid, Avenida de América station.
The distance between Santander and Madrid Airport (MAD) is 331.1 km. The road distance is 425 km.
ALSA operates a bus from Estación de autobuses de Santander to Madrid, Avenida de América every 4 hours. Tickets cost €30–50 and the journey takes 5h 30m.