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Santander to Prague buses

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Trip Overview

The average bus between Santander and Prague takes 36h 8m and the fastest bus takes 35h 35m. The bus runs, on average, 4 times per week from Santander to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 8m
Duration
2,038 km
Distance
Kč 4,853
Average price
4 times a week
Frequency

Santander to Prague bus times

Buses run 4 times a week between Santander and Prague. The service departs Santander at 5:50 PM in the evening, which arrives into Prague at 06:10:00. All services require a transfer at Paris and take an average of 36h 8m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus36h 20m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus36h 20m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    FlixBusRegioJet35h 35m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus36h 20m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Prague.ExpandLaunch map view
  • Distance: 2,037.8 km
  • Duration: 36h 8m

What companies run services between Santander, Spain and Prague, Czechia?

You can take a bus from Estación de autobuses de Santander to Prague - Florenc Main Bus Terminal via Paris and Paris - Bercy-Seine Bus Station in around 27h 50m.

Operators