The average bus between Santarém and Portimão takes 6h 22m and the fastest bus takes 4h 25m. The bus service runs several times per day from Santarém to Portimão. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Santarém and Portimão. The earliest departure is at 1:25 AM at night, and the last departure from Santarém is at 8:45 PM which arrives into Portimão at 7:20 AM. All services require a transfer, and take on average 6h 22m. The schedules shown below are for the next available departures.

4h 40m • 1 change

4h 35m • 1 change

5h 25m • 1 change
Arrives next day

10h 35m • 1 change

9h 10m • 1 change

4h 40m • 1 change

4h 35m • 1 change

5h 25m • 1 change

9h 10m • 1 change

4h 40m • 1 change

4h 35m • 1 change

5h 25m • 1 change

9h 10m • 1 change

4h 40m • 1 change

4h 35m • 1 change

5h 25m • 1 change

9h 10m • 1 change

4h 40m • 1 change

4h 35m • 1 change
Arrives next day

10h 35m • 1 change
Want to know about travelling from Santarém to Portimão? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santarém to Portimão. However, there are services departing from Santarém station and arriving at Portimão station via Lisbon. The journey, including transfers, takes approximately 6h 22m.
Santarém to Portimão bus services, operated by FlixBus, depart from Santarem station.
Santarém to Portimão bus services, operated by FlixBus, arrive at Terminal Rodoviário de Portimão station.
Book your Santarém to Portimão bus tickets online with FlixBus.
The distance between Santarém and Portimão is 233.3 km. The road distance is 347 km.
You can take a bus from Santarem to Terminal Rodoviário de Portimão via Lisbon in around 4h 59m.