The average bus between Santarém and Setúbal takes 1h 58m and the fastest bus takes 1h 42m. The bus service runs several times per day from Santarém to Setúbal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Santarém and Setúbal. The earliest departure is at 1:25 AM at night, and the last departure from Santarém is at 8:45 PM which arrives into Setúbal at 10:37 PM. All services require a transfer, and take on average 1h 58m. The schedules shown below are for the next available departures.

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 42m • 1 change

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 42m • 1 change

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 7m • 1 change

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 47m • 1 change

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 47m • 1 change

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 47m • 1 change

3h 29m • 1 change

1h 42m • 1 change

1h 52m • 1 change

2h 47m • 1 change
Want to know about travelling from Santarém to Setúbal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santarém to Setúbal. However, there are services departing from Santarém station and arriving at Setúbal station via Lisbon. The journey, including transfers, takes approximately 1h 58m.
Santarém to Setúbal bus services, operated by FlixBus, depart from Santarem station.
Santarém to Setúbal bus services, operated by FlixBus, arrive at Avenida Dom João II station.
Book your Santarém to Setúbal bus tickets online with FlixBus and Carris Metropolitana.
The distance between Santarém and Setúbal is 80.8 km. The road distance is 120 km.
You can take a bus from Santarem to Avenida Dom João II via Estação Rodoviária de Lisboa Oriente in around 1h 46m.