The bus between Santiago and Panama City takes 5h 10m. The bus service runs several times per day from Santiago to Panama City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Santiago and Panama City. The earliest departure is at 1:40 AM at night, and the last departure from Santiago is at 2:40 PM which arrives into Panama City at 7:50 PM. All services run direct with no transfers required, and take on average 5h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from Santiago to Panama City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Santiago station and arriving at Panama City station. Services depart twice daily, and operate Once daily. The journey takes approximately 5h 10m.
Santiago to Panama City bus services, operated by Tranceibosa Bocas del Toro, depart from Santiago de Veraguas station.
Santiago to Panama City bus services, operated by Tranceibosa Bocas del Toro, arrive at Panama Albrook station.
The distance between Santiago and Panama City is 189.1 km. The road distance is 258 km.
You can take a bus from Santiago de Veraguas to Fernandez de Cordoba via Penonomé, Panama Albrook, and Albrook in around 3h 43m.