The average bus between Segrate and Domodossola takes 2h 50m and the fastest bus takes 2h 36m. The bus service runs several times per day from Segrate to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Segrate and Domodossola. The earliest departure is at 6:07 AM in the morning, and the last departure from Segrate is at 8:31 PM which arrives into Domodossola at 11:08 PM. All services require a transfer at stazione lambrate m2 and take an average of 2h 50m. The schedules shown below are for the next available departures.


2h 36m • 2 changes

2h 55m • 2 changes

2h 59m • 2 changes

2h 50m • 2 changes

2h 36m • 2 changes

2h 55m • 2 changes

2h 59m • 2 changes

2h 50m • 2 changes

2h 36m • 2 changes

2h 55m • 2 changes

2h 59m • 2 changes

2h 50m • 2 changes

2h 36m • 2 changes

2h 55m • 2 changes

2h 59m • 2 changes

2h 50m • 2 changes

2h 36m • 2 changes

2h 55m • 2 changes

2h 59m • 2 changes

2h 50m • 2 changes

2h 41m • 2 changes

2h 41m • 2 changes

2h 46m • 2 changes

2h 59m • 2 changes

3h 1m • 2 changes

3h 6m • 2 changes

2h 56m • 2 changes

2h 48m • 2 changesWant to know about travelling from Segrate to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Segrate to Domodossola. However, there are services departing from Milano Centrale station and arriving at Domodossola station via Domodossola station. The journey, including transfers, takes approximately 2h 50m.
Segrate to Domodossola bus services, operated by Trenord, depart from Milano Centrale station.
Segrate to Domodossola bus services, operated by Trenord, arrive at Domodossola station.
The distance between Segrate and Domodossola is 104.4 km. The road distance is 136 km.
Trenord operates a bus from Milano Centrale to Domodossola every 2 hours, and the journey takes 1h 43m.