The average bus between Serrano and Milan takes 22h 3m and the fastest bus takes 15h 30m. The bus service runs several times per day from Serrano to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Serrano and Milan. The earliest departure is at 2:15 PM in the afternoon, and the last departure from Serrano is at 9:00 PM which arrives into Milan at 5:45 AM. All services require a transfer at Maglie - Stazione FSE and take an average of 22h 3m. The schedules shown below are for the next available departures.
Arrives next day


15h 30m • 2 changes
Arrives next day


25h 45m • 2 changes
Arrives next day


15h 30m • 2 changes
Arrives next day


25h 45m • 2 changes
Arrives next day


15h 30m • 2 changes
Arrives next day


25h 45m • 2 changes
Want to know about travelling from Serrano to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Serrano to Milan. However, there are services departing from Serrano station and arriving at Milan station via Milano, San Donato M3. The journey, including transfers, takes approximately 22h 3m.
Serrano to Milan bus services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., depart from Lecce station.
Serrano to Milan bus services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., arrive at Milano, San Donato M3 station.
Book your Serrano to Milan bus tickets online with Ferrovie del Sud Est e Servizi Automobilistici S.r.l., Salento in bus and FlixBus.
The distance between Serrano and Milan is 949.3 km. The road distance is 1,086 km.
FlixBus operates a bus from Lecce to Milano, San Donato M3 once daily. Tickets cost €85–150 and the journey takes 13h 15m.