The average bus between Setúbal and Loulé takes 7h 37m and the fastest bus takes 4h 50m. The bus service runs several times per day from Setúbal to Loulé. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Setúbal and Loulé. The earliest departure is at 10:35 AM in the morning, and the last departure from Setúbal is at 8:35 PM which arrives into Loulé at 11:50 AM. All services require a transfer, and take on average 7h 37m. The schedules shown below are for the next available departures.

5h • 1 change

6h 5m • 1 change

4h 50m • 1 change
Arrives next day

16h • 1 change

5h • 1 change

6h 5m • 1 change

4h 50m • 1 change
Arrives next day

16h • 1 change

5h • 1 change

6h 5m • 1 change

4h 50m • 1 change
Arrives next day

16h • 1 change

5h • 1 change

6h 5m • 1 change

4h 50m • 1 change
Arrives next day

16h • 1 change
Want to know about travelling from Setúbal to Loulé? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Setúbal to Loulé. However, there are services departing from Setúbal station and arriving at Loulé station via Estação Rodoviária de Sete Rios. The journey, including transfers, takes approximately 7h 37m.
Setúbal to Loulé bus services, operated by Rede Expressos, depart from Interface de Transportes de Setúbal station.
Setúbal to Loulé bus services, operated by Rede Expressos, arrive at Terminal Rodoviário de Loulé station.
Book your Setúbal to Loulé bus tickets online with Rede Expressos.
The distance between Setúbal and Loulé is 172 km. The road distance is 334 km.
You can take a bus from Interface de Transportes de Setúbal to Terminal Rodoviário de Loulé via Estação Rodoviária de Sete Rios in around 5h 15m.