The average bus between Setauket-East Setauket and Southold takes 3h 21m and the fastest bus takes 2h 26m. There is a bus service every few hours from Setauket-East Setauket to Southold. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Setauket-East Setauket and Southold. The earliest departure is at 6:16 AM in the morning, and the last departure from Setauket-East Setauket is at 10:53 PM which arrives into Southold at 7:40 AM. All services require a transfer at Port Jefferson LIRR and take an average of 3h 21m. The schedules shown below are for the next available departures.


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2h 28m • 2 changes


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2h 36m • 2 changes


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2h 36m • 2 changes


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2h 36m • 2 changes
Want to know about travelling from Setauket-East Setauket to Southold? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Setauket-East Setauket to Southold. However, there are services departing from Setauket-East Setauket station and arriving at Southold station via Riverhead LIRR. The journey, including transfers, takes approximately 3h 21m.
Setauket-East Setauket to Southold bus services, operated by Suffolk County Transit, depart from Port Jefferson LIRR station.
Setauket-East Setauket to Southold bus services, operated by Suffolk County Transit, arrive at NYS 25/Youngs Ave station.
The distance between Setauket-East Setauket and Southold is 58.6 km. The road distance is 79 km.
You can take a bus from NYS 25A/The Hills Dr to NYS 25/Youngs Ave via Port Jefferson LIRR and Riverhead LIRR in around 3h 14m.