Rome2Rio

Setúbal to Rome buses

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Trip Overview

The bus between Setúbal and Rome takes 42h 30m. There is at least one bus per day from Setúbal to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 30m
Duration
2,601 km
Distance
€262
Average price
Once daily
Frequency

Setúbal to Rome bus times

Buses run once daily between Setúbal and Rome. The service departs Setúbal at 1:45 PM in the afternoon, which arrives into Rome at 09:15:00. All services require a transfer, and take on average 42h 30m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    ALSAFlixBus42h 30m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    ALSAFlixBus42h 30m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    ALSAFlixBus42h 30m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    ALSAFlixBus42h 30m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    ALSAFlixBus42h 30m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    ALSAFlixBus42h 30m • 1 change

Frequently asked questions

Want to know about travelling from Setúbal to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Setúbal to Rome.ExpandLaunch map view
  • Distance: 2,600.7 km
  • Duration: 42h 30m

What companies run services between Setúbal, Portugal and Rome, Italy?

You can take a bus from Interface de Transportes de Setúbal to Roma, Autostazione Tiburtina via Marseille, Gare de Marseille-Saint-Charles in around 40h.

Operators