The average bus between Seville and Santillana del Mar takes 21h 1m and the fastest bus takes 15h 45m. The bus service runs several times per day from Seville to Santillana del Mar. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Seville and Santillana del Mar. The earliest departure is at 8:00 AM in the morning, and the last departure from Seville is at 11:20 PM which arrives into Santillana del Mar at 3:05 PM. All services require a transfer at Salamanca, Estación de Autobuses and take an average of 21h 1m. The schedules shown below are for the next available departures.
Arrives next day


25h 20m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


25h 20m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


25h 20m • 2 changes
Arrives next day


15h 45m • 2 changes
Arrives next day


26h 15m • 2 changes
Arrives next day


17h 45m • 2 changes
Want to know about travelling from Seville to Santillana del Mar? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Seville to Santillana del Mar. However, there are services departing from Seville station and arriving at Santillana del Mar station via Salamanca, Estación de Autobuses. The journey, including transfers, takes approximately 21h 1m.
Seville to Santillana del Mar bus services, operated by ALSA, depart from Sevilla, Estación de Autobuses (Plaza de Armas) station.
Seville to Santillana del Mar bus services, operated by ALSA, arrive at Torrelavega station.
The distance between Seville and Santillana del Mar is 686.4 km. The road distance is 818 km.
You can take a bus from Sevilla, Estación de Autobuses (Plaza de Armas) to Santillana Del Mar via Salamanca, Estación de Autobuses and Torrelavega in around 13h 15m.