The average bus between Shepherd's Bush and Manchester Piccadilly Station takes 5h 21m and the fastest bus takes 4h 55m. There is a bus service every few hours from Shepherd's Bush to Manchester Piccadilly Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Shepherd's Bush and Manchester Piccadilly Station. The earliest departure is at 6:40 AM in the morning, and the last departure from Shepherd's Bush is at 8:30 PM which arrives into Manchester Piccadilly Station at 2:00 AM. All services require a transfer at Marble Arch and take an average of 5h 21m. The schedules shown below are for the next available departures.


5h 26m • 2 changes


5h 37m • 2 changes


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5h 17m • 2 changes


6h • 2 changes


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5h 13m • 2 changes


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5h 59m • 2 changes
Want to know about travelling from Shepherd's Bush to Manchester Piccadilly Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Shepherd's Bush to Manchester Piccadilly Station. However, there are services departing from Shepherd's Bush station and arriving at Manchester Piccadilly Station station via Manchester, Shudehill Interchange. The journey, including transfers, takes approximately 5h 21m.
Shepherd's Bush to Manchester Piccadilly Station bus services, operated by First Bus London, depart from London, Finchley Road ("Subway" restaurant) station.
Shepherd's Bush to Manchester Piccadilly Station bus services, operated by First Bus London, arrive at Manchester, Shudehill Interchange station.
The distance between Shepherd's Bush and Manchester Piccadilly Station is 258.1 km. The road distance is 320 km.
FlixBus operates a bus from London, Finchley Road ("Subway" restaurant) to Manchester, Shudehill Interchange hourly. Tickets cost £23–40 and the journey takes 4h 10m.