The average bus between Sicily and Florence takes 18h 1m and the fastest bus takes 17h 45m. The bus service runs several times per day from Sicily to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Sicily and Florence. The earliest departure is at 2:56 PM in the afternoon, and the last departure from Sicily is at 8:40 PM which arrives into Florence at 2:55 PM. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 18h 1m. The schedules shown below are for the next available departures.
Arrives next day

17h 45m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

17h 45m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

17h 45m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

17h 49m • 1 change
Arrives next day

18h 20m • 1 change
Arrives next day

17h 49m • 1 change
Arrives next day

18h 20m • 1 change
Want to know about travelling from Sicily to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sicily to Florence. However, there are services departing from Sicily station and arriving at Florence station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 18h 1m.
Sicily to Florence bus services, operated by AMAT Palermo S.p.A., depart from Palermo station.
Sicily to Florence bus services, operated by AMAT Palermo S.p.A., arrive at Florence Villa Constanza Bus Station.
The distance between Sicily and Florence is 730.7 km. The road distance is 1,278 km.
FlixBus operates a bus from Palermo to Florence Villa Constanza Bus Station twice daily. Tickets cost €110–180 and the journey takes 17h 20m.