The average bus between Sicily and Isola Ortigia takes 4h 12m and the fastest bus takes 4h 3m. The bus service runs several times per day from Sicily to Isola Ortigia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Sicily and Isola Ortigia. The earliest departure is at 7:11 AM in the morning, and the last departure from Sicily is at 4:12 PM which arrives into Isola Ortigia at 8:25 PM. All services require a transfer, and take on average 4h 12m. The schedules shown below are for the next available departures.

4h 13m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 13m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 13m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 13m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 12m • 1 change
Want to know about travelling from Sicily to Isola Ortigia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sicily to Isola Ortigia. However, there are services departing from Sicily station and arriving at Isola Ortigia station via Siracusa Bus Terminal. The journey, including transfers, takes approximately 4h 12m.
Sicily to Isola Ortigia bus services, operated by AMAT Palermo S.p.A., depart from Palermo Via Oreto 385 station.
Sicily to Isola Ortigia bus services, operated by AMAT Palermo S.p.A., arrive at Siracusa Bus Terminal station.
The distance between Sicily and Isola Ortigia is 116.5 km. The road distance is 266 km.
Interbus operates a bus from Palermo Via Oreto 385 to Siracusa Bus Terminal 4 times a day. Tickets cost €13–35 and the journey takes 3h 20m.