The average bus between Sicily and La Spezia takes 23h 30m and the fastest bus takes 22h 30m. There is at least one bus per day from Sicily to La Spezia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Sicily and La Spezia. The earliest departure is at 2:56 PM in the afternoon, and the last departure from Sicily is at 8:40 PM which arrives into La Spezia at 7:10 PM. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 23h 30m. The schedules shown below are for the next available departures.
Arrives next day


24h 10m • 2 changes
Arrives next day


22h 30m • 2 changes
Arrives next day


24h 10m • 2 changes
Arrives next day


22h 30m • 2 changes
Want to know about travelling from Sicily to La Spezia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sicily to La Spezia. However, there are services departing from Sicily station and arriving at La Spezia station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 23h 30m.
Sicily to La Spezia bus services, operated by AMAT Palermo S.p.A., depart from Palermo station.
Sicily to La Spezia bus services, operated by AMAT Palermo S.p.A., arrive at La Spezia station.
The distance between Sicily and La Spezia is 810.6 km. The road distance is 1,417 km.
You can take a bus from Piazza Boiardo to La Spezia via Stazione Centrale Pensilina Esterna, Palermo, and Florence Villa Constanza Bus Station in around 21h 30m.