Rome2Rio

Sicily to Milan buses

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Trip Overview

The bus between Sicily and Milan takes 22h 49m. There is at least one bus per day from Sicily to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 49m
Duration
1,596 km
Distance
€161
Average price
Once daily
Frequency

Sicily to Milan bus times

Buses run once daily between Sicily and Milan. The earliest departure is at 2:55 PM in the afternoon, and the last departure from Sicily is at 2:56 PM which arrives into Milan at 1:45 PM. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 22h 49m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 50m • 1 change

Departing Tuesday, October 13, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 50m • 1 change

Departing Wednesday, October 14, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 50m • 1 change

Departing Thursday, October 15, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 50m • 1 change

Departing Friday, October 16, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 50m • 1 change

Departing Saturday, October 17, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 50m • 1 change

Departing Sunday, October 18, 2026

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    Arrives next day

    AMAT Palermo S.p.A.FlixBus22h 49m • 1 change

Frequently asked questions

Want to know about travelling from Sicily to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Sicily to Milan.ExpandLaunch map view
  • Distance: 1,596.2 km
  • Duration: 22h 49m

What companies run services between Sicily, Italy and Milan, Italy?

FlixBus operates a bus from Palermo to Milano, Autostazione Lampugnano once daily. Tickets cost €130–200 and the journey takes 22h 20m.

Operators