Rome2Rio

Sicily to Syracuse (Region) buses

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Trip Overview

The average bus between Sicily and Syracuse (Region) takes 4h 35m and the fastest bus takes 4h 9m. The bus service runs several times per day from Sicily to Syracuse (Region). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 35m
Duration
270 km
Distance
€23
Average price
Twice daily
Frequency

Sicily to Syracuse (Region) bus times

Buses run twice daily between Sicily and Syracuse (Region). The earliest departure is at 10:24 AM in the morning, and the last departure from Sicily is at 2:56 PM which arrives into Syracuse (Region) at 7:05 PM. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 4h 35m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 10m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 10m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 10m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h 11m • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 9m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 10m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 10m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus5h • 2 changes
  •  → 

    AMAT Palermo S.p.A.FlixBusInterbus4h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Sicily to Syracuse (Region)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Sicily to Syracuse (Region).ExpandLaunch map view
  • Distance: 269.8 km
  • Duration: 4h 35m

What companies run services between Sicily, Italy and Syracuse (Region), Italy?

You can take a bus from Piazza Boiardo to Siracusa - v.le Scala Greca via Stazione Centrale Pensilina Esterna, Palermo Via Tommaso Fazello, and Catania Airport in around 5h 6m.

Operators