Rome2Rio

Siena Cathedral to Rome buses

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Trip Overview

The average bus between Siena Cathedral and Rome takes 3h 2m and the fastest bus takes 3h. The bus service runs several times per day from Siena Cathedral to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 2m
Duration
232 km
Distance
€22
Average price
Twice daily
Frequency

Siena Cathedral to Rome bus times

Buses run twice daily between Siena Cathedral and Rome. The earliest departure is at 6:50 AM in the morning, and the last departure from Siena Cathedral is at 10:35 AM which arrives into Rome at 1:35 PM. All services run direct with no transfers required, and take on average 3h 2m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

  •  → 

    bus bus 3h 5m • Direct
  •  → 

    bus bus 3h • Direct

Departing Saturday, October 10, 2026

  •  → 

    bus bus 3h 5m • Direct
  •  → 

    bus bus 3h • Direct

Departing Sunday, October 11, 2026

  •  → 

    bus bus 3h 5m • Direct
  •  → 

    bus bus 3h • Direct

Departing Monday, October 12, 2026

  •  → 

    bus bus 3h 5m • Direct
  •  → 

    bus bus 3h • Direct

Departing Tuesday, October 13, 2026

  •  → 

    bus bus 3h 5m • Direct
  •  → 

    bus bus 3h • Direct

Departing Wednesday, October 14, 2026

  •  → 

    bus bus 3h 5m • Direct
  •  → 

    bus bus 3h • Direct

Frequently asked questions

Want to know about travelling from Siena Cathedral to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Siena Cathedral to Rome.ExpandLaunch map view
  • Distance: 232.4 km
  • Duration: 3h 2m

What companies run services between Siena Cathedral, Tuscany, Italy and Rome, Italy?

FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina twice daily. Tickets cost €19–29 and the journey takes 3h.

Operators