The average bus between Siena and Acquasanta Terme takes 8h 39m and the fastest bus takes 5h 55m. The bus service runs several times per day from Siena to Acquasanta Terme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Siena and Acquasanta Terme. The earliest departure is at 10:45 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Acquasanta Terme at 9:50 AM. All services require a transfer, and take on average 8h 39m. The schedules shown below are for the next available departures.

5h 55m • 1 change

7h 10m • 1 change
Arrives next day

11h 25m • 1 change

5h 55m • 1 change

7h 10m • 1 change
Arrives next day

11h 25m • 1 change

5h 55m • 1 change

7h 10m • 1 change
Arrives next day

11h 25m • 1 change
Want to know about travelling from Siena to Acquasanta Terme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Acquasanta Terme. However, there are services departing from Siena station and arriving at Acquasanta Terme station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h 39m.
Siena to Acquasanta Terme bus services, operated by FlixBus, depart from Siena station.
Siena to Acquasanta Terme bus services, operated by FlixBus, arrive at Acquasanta Terme station.
The distance between Siena and Acquasanta Terme is 179.6 km. The road distance is 402 km.
You can take a bus from Siena to Acquasanta Terme via Roma, Autostazione Tiburtina in around 6h 40m.