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Siena to Alessandria buses

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Trip Overview

The bus between Siena and Alessandria takes 10h. The bus runs, on average, 5 times per week from Siena to Alessandria. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h
Duration
376 km
Distance
€40
Average price
5 times a week
Frequency

Siena to Alessandria bus times

Buses run 5 times a week between Siena and Alessandria. The service departs Siena at 8:25 PM in the evening, which arrives into Alessandria at 06:25:00. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 10h. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    FlixBusFlixBusFlixBus10h • 2 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    FlixBusFlixBusFlixBus10h • 2 changes

Departing Friday, November 6, 2026

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    Arrives next day

    FlixBusFlixBusFlixBus10h • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    FlixBusFlixBusFlixBus10h • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    FlixBusFlixBusFlixBus10h • 2 changes

Frequently asked questions

Want to know about travelling from Siena to Alessandria? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Siena to Alessandria.ExpandLaunch map view
  • Distance: 376.1 km
  • Duration: 10h

What companies run services between Siena, Italy and Alessandria, Italy?

You can take a bus from Siena to Alessandria via Florence Villa Constanza Bus Station and Genoa in around 6h 35m.

Operators