The average bus between Siena and Casalecchio di Reno takes 4h 20m and the fastest bus takes 2h 52m. The bus service runs several times per day from Siena to Casalecchio di Reno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Siena and Casalecchio di Reno. The earliest departure is at 7:50 AM in the morning, and the last departure from Siena is at 6:40 PM which arrives into Casalecchio di Reno at 1:52 AM. All services require a transfer, and take on average 4h 20m. The schedules shown below are for the next available departures.

3h 6m • 1 change
4h 12m • 1 change
3h 35m • 1 change
3h 13m • 1 changeWant to know about travelling from Siena to Casalecchio di Reno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Casalecchio di Reno. However, there are services departing from Siena station and arriving at Bologna Centrale station via Bologna Centrale station. The journey, including transfers, takes approximately 4h 20m.
Siena to Casalecchio di Reno bus services, operated by FlixBus, depart from Siena station.
Siena to Casalecchio di Reno bus services, operated by FlixBus, arrive at Bologna Centrale station.
The distance between Siena and Casalecchio di Reno is 128.8 km. The road distance is 162 km.
FlixBus operates a bus from Siena to Bologna Centrale every 2 hours. Tickets cost €14–22 and the journey takes 2h 30m.