The average bus between Siena and Medicina takes 4h 31m and the fastest bus takes 3h 10m. The bus service runs several times per day from Siena to Medicina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Siena and Medicina. The earliest departure is at 6:30 AM in the morning, and the last departure from Siena is at 6:40 PM which arrives into Medicina at 6:48 AM. All services require a transfer, and take on average 4h 31m. The schedules shown below are for the next available departures.

3h 36m • 1 change
3h 22m • 1 change
4h 2m • 1 change
3h 49m • 1 change
3h 12m • 1 change
3h 36m • 1 change
3h 22m • 1 change
4h 2m • 1 change
3h 42m • 1 change
3h 36m • 1 change
3h 52m • 1 change
4h 2m • 1 change
3h 35m • 1 change
3h 45m • 1 change
4h • 1 change
3h 50m • 1 change
3h 12m • 1 change
3h 36m • 1 change
3h 22m • 1 change
4h 2m • 1 change
3h 22m • 1 change
3h 36m • 1 change
3h 22m • 1 change
4h 2m • 1 changeWant to know about travelling from Siena to Medicina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Medicina. However, there are services departing from Siena station and arriving at Medicina station via Bologna Centrale. The journey, including transfers, takes approximately 4h 31m.
Siena to Medicina bus services, operated by FlixBus, depart from Siena station.
Siena to Medicina bus services, operated by FlixBus, arrive at Medicina Fronte Stazione station.
The distance between Siena and Medicina is 131.1 km. The road distance is 193 km.
You can take a bus from Siena to Medicina Fronte Stazione via Bologna Autostazione in around 3h 41m.