The average bus between Siena and Montepulciano takes 3h 45m and the fastest bus takes 1h 58m. The bus service runs several times per day from Siena to Montepulciano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Siena and Montepulciano. The earliest departure is at 6:52 AM in the morning, and the last departure from Siena is at 9:18 PM which arrives into Montepulciano at 7:48 AM. All services require a transfer, and take on average 3h 45m. The schedules shown below are for the next available departures.

2h 1m • 1 change

4h 51m • 1 change

1h 58m • 1 change

2h 3m • 1 change

2h 1m • 1 change

4h 51m • 1 change

1h 58m • 1 change

2h 3m • 1 change

2h 1m • 1 change

4h 51m • 1 change

1h 58m • 1 change

2h 3m • 1 change

2h 1m • 1 change

4h 51m • 1 change

1h 58m • 1 change

2h 3m • 1 change

2h 1m • 1 change

4h 51m • 1 change

1h 58m • 1 change

2h 3m • 1 change
Want to know about travelling from Siena to Montepulciano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Montepulciano. However, there are services departing from Siena station and arriving at Montepulciano station via Buonconvento. The journey, including transfers, takes approximately 3h 45m.
Siena to Montepulciano bus services, operated by Autolinee Toscane, depart from Porta Pispini station.
Siena to Montepulciano bus services, operated by Autolinee Toscane, arrive at P.Ta Delle Farine station.
The distance between Siena and Montepulciano is 44.3 km. The road distance is 71 km.
You can take a bus from Porta Pispini to P.Ta Delle Farine via Buonconvento in around 2h 28m.