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Siena to Piazza del Duomo buses

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Trip Overview

The average bus between Siena and Piazza del Duomo takes 8h 25m and the fastest bus takes 5h 8m. The bus service runs several times per day from Siena to Piazza del Duomo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 25m
Duration
367 km
Distance
€39
Average price
Twice daily
Frequency

Siena to Piazza del Duomo bus times

Buses run twice daily between Siena and Piazza del Duomo. The earliest departure is at 12:45 AM at night, and the last departure from Siena is at 4:05 PM which arrives into Piazza del Duomo at 1:02 AM. All services require a transfer at Milano, San Donato M3 and take an average of 8h 25m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    FlixBusATM5h 8m • 1 change
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    Arrives next day

    FlixBusATM8h 57m • 1 change

Departing Monday, November 9, 2026

  •  → 

    FlixBusATM5h 8m • 1 change
  •  → 

    Arrives next day

    FlixBusATM8h 57m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    FlixBusATM5h 8m • 1 change
  •  → 

    Arrives next day

    FlixBusATM15h 42m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    FlixBusATM5h 8m • 1 change
  •  → 

    Arrives next day

    FlixBusATM18h 52m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    FlixBusATM5h 8m • 1 change
  •  → 

    Arrives next day

    FlixBusATM8h 57m • 1 change

Departing Friday, November 13, 2026

  •  → 

    FlixBusATM5h 8m • 1 change

Frequently asked questions

Want to know about travelling from Siena to Piazza del Duomo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Siena to Piazza del Duomo.ExpandLaunch map view
  • Distance: 366.8 km
  • Duration: 8h 25m

What companies run services between Siena, Italy and Piazza del Duomo, Lombardy, Italy?

FlixBus operates a bus from Siena to Milano, San Donato M3 every 4 hours. Tickets cost €30–50 and the journey takes 4h 30m.

Operators