The average bus between Siena and Port of Naples takes 6h 14m and the fastest bus takes 5h 57m. The bus service runs several times per day from Siena to Port of Naples. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Siena and Port of Naples. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 9:00 PM which arrives into Port of Naples at 3:22 AM. All services require a transfer at Napoli P.zza Garibaldi and take an average of 6h 14m. The schedules shown below are for the next available departures.

6h 27m • 1 change

5h 57m • 1 change

6h 12m • 1 change
Arrives next day

6h 22m • 1 change

6h 22m • 1 change

5h 57m • 1 change

6h 12m • 1 change
Arrives next day

6h 22m • 1 change

6h 27m • 1 change

6h 7m • 1 change

6h 22m • 1 change
Arrives next day

6h 22m • 1 change
Want to know about travelling from Siena to Port of Naples? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Port of Naples. However, there are services departing from Siena station and arriving at Port of Naples station via Napoli P.zza Garibaldi. The journey, including transfers, takes approximately 6h 14m.
Siena to Port of Naples bus services, operated by FlixBus, depart from Siena station.
Siena to Port of Naples bus services, operated by FlixBus, arrive at Napoli P.zza Garibaldi station.
The distance between Siena and Port of Naples is 367.5 km. The road distance is 451 km.
FlixBus operates a bus from Siena to Napoli P.zza Garibaldi 3 times a day. Tickets cost €35–65 and the journey takes 5h 40m.