The average bus between Siena and Province of Rome (Region) takes 4h 52m and the fastest bus takes 3h 30m. The bus service runs several times per day from Siena to Province of Rome (Region). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Siena and Province of Rome (Region). The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Province of Rome (Region) at 6:40 AM. All services require a transfer, and take on average 4h 52m. The schedules shown below are for the next available departures.

3h 45m • 1 change

3h 50m • 1 change

3h 30m • 1 change
Arrives next day

10h 12m • 1 change

5h 2m • 1 change

3h 52m • 1 change

4h 22m • 1 change

5h 27m • 1 change

5h 2m • 1 change

3h 52m • 1 change

4h 22m • 1 change

5h 27m • 1 change

3h 45m • 1 change

4h 30m • 1 change

4h 45m • 1 change

3h 45m • 1 change

3h 45m • 1 change

4h 30m • 1 change

4h 45m • 1 change

3h 45m • 1 change

3h 45m • 1 change

4h 30m • 1 change

4h 45m • 1 change

3h 45m • 1 change

3h 45m • 1 change

4h 30m • 1 change

4h 45m • 1 change

3h 45m • 1 change
Want to know about travelling from Siena to Province of Rome (Region)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Province of Rome (Region). However, there are services departing from Siena station and arriving at Province of Rome (Region) station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 52m.
Siena to Province of Rome (Region) bus services, operated by FlixBus, depart from Siena station.
Siena to Province of Rome (Region) bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Siena and Province of Rome (Region) is 185.8 km. The road distance is 248 km.
FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina every 3 hours. Tickets cost €20–35 and the journey takes 2h 50m. AutoLinee Moretti also services this route 3 times a week.