Siena to Province of Rome (Region) Buses

Siena to Province of Rome (Region) buses

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Trip Overview

The average bus between Siena and Province of Rome (Region) takes 4h 32m and the fastest bus takes 3h 30m. The bus service runs several times per day from Siena to Province of Rome (Region). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 32m
Duration: 248 km
Distance: €22
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Siena to Roma, Autostazione Tiburtinabus 1520 / ...

4h 7m

€17–32

Siena to Province of Rome (Region) bus times

Buses run every 4 hours between Siena and Province of Rome (Region). The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Province of Rome (Region) at 6:40 AM. All services require a transfer, and take on average 4h 32m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

10:25 PM → 6:40 AM
Arrives next day
8h 15m • 1 change

Departing Saturday, November 7, 2026

5:35 AM → 9:20 AM
3h 45m • 1 change
7:00 AM → 11:30 AM
4h 30m • 1 change
8:45 AM → 1:30 PM
4h 45m • 1 change
10:45 AM → 2:40 PM
3h 55m • 1 change
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Departing Sunday, November 8, 2026

5:35 AM → 10:37 AM
5h 2m • 1 change
8:45 AM → 12:37 PM
3h 52m • 1 change
10:45 AM → 3:07 PM
4h 22m • 1 change
12:40 PM → 6:07 PM
5h 27m • 1 change
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Departing Monday, November 9, 2026

5:35 AM → 9:22 AM
3h 47m • 1 change
7:00 AM → 11:32 AM
4h 32m • 1 change
8:45 AM → 12:32 PM
3h 47m • 1 change
10:45 AM → 2:37 PM
3h 52m • 1 change
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Departing Tuesday, November 10, 2026

5:35 AM → 9:22 AM
3h 47m • 1 change
7:00 AM → 11:32 AM
4h 32m • 1 change
8:45 AM → 12:32 PM
3h 47m • 1 change
10:45 AM → 2:37 PM
3h 52m • 1 change
Show more

Departing Wednesday, November 11, 2026

5:35 AM → 9:22 AM
3h 47m • 1 change
7:00 AM → 11:32 AM
4h 32m • 1 change
8:45 AM → 12:32 PM
3h 47m • 1 change
10:45 AM → 2:37 PM
3h 52m • 1 change
Show more

Departing Thursday, November 12, 2026

5:35 AM → 9:22 AM
3h 47m • 1 change
7:00 AM → 11:32 AM
4h 32m • 1 change
8:45 AM → 12:32 PM
3h 47m • 1 change
10:45 AM → 2:37 PM
3h 52m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Siena to Province of Rome (Region)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Siena to Province of Rome (Region) buses

Trip Overview

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