The average bus between Siena and Puglia takes 2h 6m and the fastest bus takes 1h 26m. The bus service runs several times per day from Siena to Puglia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Siena and Puglia. The earliest departure is at 6:27 AM in the morning, and the last departure from Siena is at 6:29 PM which arrives into Puglia at 7:55 PM. All services require a transfer at Arezzo Terminal and take an average of 2h 6m. The schedules shown below are for the next available departures.

2h 45m • 1 change

1h 52m • 1 change

2h 2m • 1 change

2h • 1 change

2h 45m • 1 change

1h 52m • 1 change

2h 2m • 1 change

2h • 1 change

2h 45m • 1 change

1h 52m • 1 change

2h 2m • 1 change

2h • 1 change

2h 45m • 1 change

1h 52m • 1 change

2h 2m • 1 change

2h • 1 change

2h 35m • 1 change

1h 52m • 1 change

2h 2m • 1 change

2h • 1 change
Want to know about travelling from Siena to Puglia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Puglia. However, there are services departing from Siena station and arriving at Puglia station via Arezzo Terminal. The journey, including transfers, takes approximately 2h 6m.
Siena to Puglia bus services, operated by Autolinee Toscane, depart from Porta Pispini station.
Siena to Puglia bus services, operated by Autolinee Toscane, arrive at Arezzo Terminal station.
The distance between Siena and Puglia is 49 km. The road distance is 81 km.
Autolinee Toscane operates a bus from Porta Pispini to Arezzo Terminal every 4 hours. Tickets cost €5–7 and the journey takes 1h 25m.