The average bus between Siena and San Donato Milanese takes 5h 59m and the fastest bus takes 5h 14m. The bus service runs several times per day from Siena to San Donato Milanese. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Siena and San Donato Milanese. The earliest departure is at 12:45 AM at night, and the last departure from Siena is at 6:10 PM which arrives into San Donato Milanese at 11:28 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 5h 59m. The schedules shown below are for the next available departures.


6h 18m • 2 changes


5h 20m • 2 changes


5h 38m • 2 changes


7h 6m • 2 changes


5h 19m • 2 changes


5h 18m • 2 changes


5h 20m • 2 changes


5h 38m • 2 changes


5h 23m • 2 changes


5h 14m • 2 changes


5h 35m • 2 changes


5h 35m • 2 changes


6h 39m • 2 changes


5h 14m • 2 changes


5h 35m • 2 changes


5h 35m • 2 changes


5h 19m • 2 changes


5h 18m • 2 changes


5h 20m • 2 changes


5h 38m • 2 changes


5h 19m • 2 changes


5h 40m • 2 changes


5h 38m • 2 changes


7h 6m • 2 changes
Want to know about travelling from Siena to San Donato Milanese? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to San Donato Milanese. However, there are services departing from Siena station and arriving at San Donato Milanese station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 5h 59m.
Siena to San Donato Milanese bus services, operated by FlixBus, depart from Siena station.
Siena to San Donato Milanese bus services, operated by FlixBus, arrive at Milano, San Donato M3 station.
The distance between Siena and San Donato Milanese is 284.6 km. The road distance is 362 km.
You can take a bus from Siena to p.za tevere via Florence Villa Constanza Bus Station and Milano, San Donato M3 in around 5h 36m.