Bus Siena to Vatican City from €28 | Tickets & Timetables

Siena to Vatican City buses

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Trip Overview

The average bus between Siena and Vatican City takes 4h 1m and the fastest bus takes 3h 22m. The bus service runs several times per day from Siena to Vatican City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 1m
Duration: 239 km
Distance: €28
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Siena to Roma, Autostazione Tiburtinabus 1520 / ...

3h 34m

€17–41

Siena to Vatican City bus times

Buses run every 3 hours between Siena and Vatican City. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Vatican City at 5:57 AM. All services require a transfer, and take on average 4h 1m. The schedules shown below are for the next available departures.

Departing Tuesday, August 11, 2026

3:00 PM → 6:36 PM
3h 36m • 1 change
3:45 PM → 7:21 PM
3h 36m • 1 change
9:00 PM → 12:32 AM
Arrives next day
3h 32m • 1 change
10:25 PM → 5:57 AM
Arrives next day
7h 32m • 1 change

Departing Wednesday, August 12, 2026

5:35 AM → 9:35 AM
4h • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:11 PM
3h 26m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
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Departing Thursday, August 13, 2026

5:35 AM → 9:35 AM
4h • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:11 PM
3h 26m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
Show more

Departing Friday, August 14, 2026

5:35 AM → 9:35 AM
4h • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:11 PM
3h 26m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
Show more

Departing Saturday, August 15, 2026

5:35 AM → 9:20 AM
3h 45m • 1 change
7:00 AM → 10:41 AM
3h 41m • 1 change
8:45 AM → 12:12 PM
3h 27m • 1 change
10:45 AM → 2:16 PM
3h 31m • 1 change
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Departing Sunday, August 16, 2026

5:35 AM → 9:20 AM
3h 45m • 1 change
7:00 AM → 10:41 AM
3h 41m • 1 change
8:45 AM → 12:12 PM
3h 27m • 1 change
10:45 AM → 2:16 PM
3h 31m • 1 change
Show more

Departing Monday, August 17, 2026

5:35 AM → 9:35 AM
4h • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change

Frequently asked questions

Want to know about travelling from Siena to Vatican City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.