Siena to Vatican City Buses

Siena to Vatican City buses

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Trip Overview

The average bus between Siena and Vatican City takes 3h 55m and the fastest bus takes 3h 17m. The bus service runs several times per day from Siena to Vatican City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 55m
Duration: 238 km
Distance: €28
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Siena to Roma, Autostazione Tiburtinabus 1520 / ...

3h 31m

€17–39

Siena to Vatican City bus times

Buses run every 3 hours between Siena and Vatican City. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Vatican City at 5:46 AM. All services require a transfer, and take on average 3h 55m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

5:35 AM → 9:25 AM
3h 50m • 1 change
7:00 AM → 10:43 AM
3h 43m • 1 change
8:45 AM → 12:15 PM
3h 30m • 1 change
10:45 AM → 2:23 PM
3h 38m • 1 change
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Departing Saturday, November 7, 2026

5:35 AM → 9:26 AM
3h 51m • 1 change
7:00 AM → 10:41 AM
3h 41m • 1 change
8:45 AM → 12:03 PM
3h 18m • 1 change
10:45 AM → 2:18 PM
3h 33m • 1 change
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Departing Sunday, November 8, 2026

5:35 AM → 9:34 AM
3h 59m • 1 change
7:00 AM → 10:38 AM
3h 38m • 1 change
8:45 AM → 12:10 PM
3h 25m • 1 change
10:45 AM → 2:26 PM
3h 41m • 1 change
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Departing Monday, November 9, 2026

5:35 AM → 9:23 AM
3h 48m • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:13 PM
3h 28m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
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Departing Tuesday, November 10, 2026

5:35 AM → 9:23 AM
3h 48m • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:13 PM
3h 28m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
Show more

Departing Wednesday, November 11, 2026

5:35 AM → 9:23 AM
3h 48m • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:13 PM
3h 28m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
Show more

Departing Thursday, November 12, 2026

5:35 AM → 9:23 AM
3h 48m • 1 change
7:00 AM → 10:42 AM
3h 42m • 1 change
8:45 AM → 12:13 PM
3h 28m • 1 change
10:45 AM → 2:22 PM
3h 37m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Siena to Vatican City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.