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Siracusa to Palermo buses

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Trip Overview

The average bus between Siracusa and Palermo takes 4h 32m and the fastest bus takes 3h 45m. The bus service runs several times per day from Siracusa to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 32m
Duration
269 km
Distance
€25
Average price
Twice daily
Frequency

Siracusa to Palermo bus times

Buses run twice daily between Siracusa and Palermo. The earliest departure is at 7:15 AM in the morning, and the last departure from Siracusa is at 2:00 PM which arrives into Palermo at 7:20 PM. All services require a transfer at Catania Airport and take an average of 4h 32m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    InterbusFlixBus5h 20m • 1 change

Departing Tuesday, November 10, 2026

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    FlixBusFlixBus3h 45m • 1 change
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    InterbusFlixBus5h 20m • 1 change

Departing Wednesday, November 11, 2026

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    FlixBusFlixBus3h 45m • 1 change
  •  → 

    InterbusFlixBus5h 20m • 1 change

Departing Thursday, November 12, 2026

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    FlixBusFlixBus3h 45m • 1 change
  •  → 

    InterbusFlixBus5h 20m • 1 change

Departing Friday, November 13, 2026

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    FlixBusFlixBus3h 45m • 1 change
  •  → 

    InterbusFlixBus5h 20m • 1 change

Departing Saturday, November 14, 2026

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    FlixBusFlixBus3h 45m • 1 change
  •  → 

    InterbusFlixBus5h 20m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    FlixBusFlixBus3h 45m • 1 change
  •  → 

    InterbusFlixBus5h 20m • 1 change

Frequently asked questions

Want to know about travelling from Siracusa to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Siracusa to Palermo.ExpandLaunch map view
  • Distance: 269 km
  • Duration: 4h 32m

What companies run services between Siracusa, Italy and Palermo, Italy?

You can take a bus from Siracusa - Corso Umberto to Palermo Via Tommaso Fazello via Catania Airport and Catania Fontanarossa Airport Bus Stop in around 4h 45m.

Operators