The average bus between Sisteron and Avignon takes 6h 35m and the fastest bus takes 3h 18m. The bus service runs several times per day from Sisteron to Avignon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Sisteron and Avignon. The earliest departure is at 8:55 AM in the morning, and the last departure from Sisteron is at 6:32 PM which arrives into Avignon at 10:41 AM. All services require a transfer, and take on average 6h 35m. The schedules shown below are for the next available departures.

3h 43m • 1 change

4h 45m • 1 change

3h 18m • 1 change
Arrives next day

13h 9m • 1 change

3h 43m • 1 change

4h 45m • 1 change

3h 18m • 1 change
Arrives next day

13h 9m • 1 change

3h 43m • 1 change

4h 45m • 1 change

3h 18m • 1 change
Arrives next day

13h 9m • 1 change

3h 43m • 1 change

4h 45m • 1 change

3h 18m • 1 change
Arrives next day

13h 9m • 1 change
Want to know about travelling from Sisteron to Avignon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sisteron to Avignon. However, there are services departing from Sisteron station and arriving at Avignon station via Gare Routière. The journey, including transfers, takes approximately 6h 35m.
Sisteron to Avignon bus services, operated by Zou! Lignes Express Régionales, depart from Gare SNCF station.
Sisteron to Avignon bus services, operated by Zou! Lignes Express Régionales, arrive at Limbert/Voie d'Insertion station.
The distance between Sisteron and Avignon is 94.8 km. The road distance is 191 km.
You can take a bus from Gare SNCF to Limbert/Voie d'Insertion via Gare Routière in around 4h 1m.