Sistine Chapel to Florence bus times
Buses run hourly between Sistine Chapel and Florence. The earliest departure is at 6:02 AM in the morning, and the last departure from Sistine Chapel is at 10:05 PM which arrives into Florence at 2:10 AM. All services require a transfer at Cavalleggeri/Fornaci and take an average of 4h 32m. The schedules shown below are for the next available departures.
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4h 12m • 1 change
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4h 11m • 1 change
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4h 19m • 1 change
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4h 35m • 1 change
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Departing Thursday, September 10, 2026
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4h 12m • 1 change
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4h 11m • 1 change
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4h 19m • 1 change
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4h 35m • 1 change
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Departing Friday, September 11, 2026
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4h 3m • 1 change
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4h • 1 change
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4h 16m • 1 change
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4h 27m • 1 change
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