The average bus between Skaneateles and Buffalo takes 5h 46m and the fastest bus takes 5h 5m. The bus service runs several times per day from Skaneateles to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Skaneateles and Buffalo. The earliest departure is at 8:34 AM in the morning, and the last departure from Skaneateles is at 9:29 PM which arrives into Buffalo at 4:00 AM. All services require a transfer at C22 and take an average of 5h 46m. The schedules shown below are for the next available departures.


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Want to know about travelling from Skaneateles to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Skaneateles to Buffalo. However, there are services departing from Skaneateles station and arriving at Buffalo station via Buffalo. The journey, including transfers, takes approximately 5h 46m.
Skaneateles to Buffalo bus services, operated by Centro, depart from Syracuse station.
Skaneateles to Buffalo bus services, operated by Centro, arrive at Buffalo station.
The distance between Skaneateles and Buffalo is 199.6 km. The road distance is 301 km.
Trailways operates a bus from Syracuse to Buffalo every 4 hours. Tickets cost $28–100 and the journey takes 3h 10m. Two other operators also service this route.