The average bus between Skaneateles and Buffalo takes 5h 59m and the fastest bus takes 5h 5m. The bus service runs several times per day from Skaneateles to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Skaneateles and Buffalo. The earliest departure is at 8:34 AM in the morning, and the last departure from Skaneateles is at 9:29 PM which arrives into Buffalo at 4:00 AM. All services require a transfer at C22 and take an average of 5h 59m. The schedules shown below are for the next available departures.


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6h 32m • 2 changes

5h 5m • 2 changes

5h 20m • 2 changesWant to know about travelling from Skaneateles to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Skaneateles to Buffalo. However, there are services departing from Syracuse station and arriving at Buffalo station via Buffalo station. The journey, including transfers, takes approximately 5h 59m.
Skaneateles to Buffalo bus services, operated by Trailways, depart from Syracuse station.
Skaneateles to Buffalo bus services, operated by Trailways, arrive at Buffalo station.
The distance between Skaneateles and Buffalo is 199.6 km. The road distance is 213 km.
Trailways operates a bus from Syracuse to Buffalo 5 times a day. Tickets cost $28–100 and the journey takes 3h 10m. Two other operators also service this route.