The average bus between Slough and Birmingham takes 3h 17m and the fastest bus takes 2h 48m. There is a bus service every few hours from Slough to Birmingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Birmingham. The earliest departure is at 12:02 AM at night, and the last departure from Slough is at 11:32 PM which arrives into Birmingham at 2:35 AM. All services require a transfer, and take on average 3h 17m. The schedules shown below are for the next available departures.

3h 16m • 1 change

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3h 29m • 1 change

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3h 21m • 1 change

3h 16m • 1 change

3h 18m • 1 change

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3h 21m • 1 change

3h 16m • 1 change

3h 18m • 1 change

3h 22m • 1 change

3h 21m • 1 change

3h 16m • 1 change
Want to know about travelling from Slough to Birmingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Birmingham. However, there are services departing from Slough station and arriving at Birmingham station via Birmingham Coach Station station. The journey, including transfers, takes approximately 3h 17m.
Slough to Birmingham bus services, operated by First Berkshire & The Thames Valley, depart from Heathrow Central Bus Station.
Slough to Birmingham bus services, operated by First Berkshire & The Thames Valley, arrive at Birmingham Coach Station.
Book your Slough to Birmingham bus tickets online with First Berkshire & The Thames Valley and National Express.
The distance between Slough and Birmingham is 140.2 km. The road distance is 193 km.
National Express operates a bus from Heathrow Central Bus Station to Birmingham Coach Station hourly. Tickets cost £21–55 and the journey takes 2h 35m.