The average bus between Slough and Newcastle-under-Lyme takes 4h 22m and the fastest bus takes 4h 7m. The bus service runs several times per day from Slough to Newcastle-under-Lyme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Slough and Newcastle-under-Lyme. The earliest departure is at 12:02 AM at night, and the last departure from Slough is at 11:32 PM which arrives into Newcastle-under-Lyme at 4:10 AM. All services require a transfer at Heathrow Central Bus Station and take an average of 4h 22m. The schedules shown below are for the next available departures.

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Want to know about travelling from Slough to Newcastle-under-Lyme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Newcastle-under-Lyme. However, there are services departing from Slough station and arriving at Newcastle-under-Lyme station via Stoke-on-Trent. The journey, including transfers, takes approximately 4h 22m.
Slough to Newcastle-under-Lyme bus services, operated by First Berkshire & The Thames Valley, depart from London Heathrow Airport station.
Slough to Newcastle-under-Lyme bus services, operated by First Berkshire & The Thames Valley, arrive at Stoke-on-Trent station.
Book your Slough to Newcastle-under-Lyme bus tickets online with First Berkshire & The Thames Valley and FlixBus.
The distance between Slough and Newcastle-under-Lyme is 199.7 km. The road distance is 268 km.
FlixBus operates a bus from London Heathrow Airport to Stoke-on-Trent every 4 hours. Tickets cost £19–35 and the journey takes 3h 30m.