The average bus between Slough and Portsmouth takes 2h 16m and the fastest bus takes 2h 3m. The bus service runs several times per day from Slough to Portsmouth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Slough and Portsmouth. The earliest departure is at 12:00 AM at night, and the last departure from Slough is at 10:30 PM which arrives into Portsmouth at 12:33 AM. All services require a transfer, and take on average 2h 16m. The schedules shown below are for the next available departures.

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2h 45m • 1 changeWant to know about travelling from Slough to Portsmouth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Portsmouth. However, there are services departing from Slough station and arriving at Portsmouth station via Heathrow Terminal 5. The journey, including transfers, takes approximately 2h 16m.
Slough to Portsmouth bus services, operated by Thames Valley Buses, depart from Wellington Street Stop A station.
Slough to Portsmouth bus services, operated by Thames Valley Buses, arrive at University of Portsmouth station.
Book your Slough to Portsmouth bus tickets online with Thames Valley Buses and National Express.
The distance between Slough and Portsmouth is 86.2 km. The road distance is 115 km.
You can take a bus from Wellington Street Stop A to University of Portsmouth via Heathrow Terminal 5 in around 3h.