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Slough to Southampton buses

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Trip Overview

The average bus between Slough and Southampton takes 2h 26m and the fastest bus takes 2h 1m. There is a bus service every few hours from Slough to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 26m
Duration
69 mi
Distance
£14
Average price
Hourly
Frequency

Line 703 bus, bus

best
  1. Take the bus from Landmark Place to Heathrow Terminal 5bus bus 703
  2. Take the bus from Heathrow Terminal 5 to Coach Stationbus bus 032 / ...
2h 31m
£12–19

Slough to Southampton bus times

Buses run hourly between Slough and Southampton. The earliest departure is at 6:54 AM in the morning, and the last departure from Slough is at 10:54 PM which arrives into Southampton at 2:00 AM. All services require a transfer, and take on average 2h 26m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

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    Thames Valley BusesNational Express2h 36m • 1 change

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    Thames Valley BusesNational Express2h 43m • 1 change

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    Arrives next day

    Thames Valley BusesNational Express2h 6m • 1 change

Departing Tuesday, October 13, 2026

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    Thames Valley BusesNational Express2h 16m • 1 change

  •  → 

    Thames Valley BusesNational Express2h 26m • 1 change

  •  → 

    Thames Valley BusesNational Express2h 26m • 1 change

  •  → 

    Thames Valley BusesNational Express2h 16m • 1 change
  • Show more

Departing Wednesday, October 14, 2026

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    Thames Valley BusesNational Express2h 16m • 1 change

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    Thames Valley BusesNational Express2h 26m • 1 change

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    Thames Valley BusesNational Express2h 26m • 1 change

  •  → 

    Thames Valley BusesNational Express2h 16m • 1 change
  • Show more

Departing Thursday, October 15, 2026

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    Thames Valley BusesNational Express2h 16m • 1 change

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    Thames Valley BusesNational Express2h 26m • 1 change

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    Thames Valley BusesNational Express2h 26m • 1 change

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    Thames Valley BusesNational Express2h 16m • 1 change
  • Show more

Departing Friday, October 16, 2026

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    Thames Valley BusesNational Express2h 16m • 1 change

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    Thames Valley BusesNational Express2h 26m • 1 change

  •  → 

    Thames Valley BusesNational Express2h 16m • 1 change

  •  → 

    Thames Valley BusesNational Express2h 41m • 1 change
  • Show more

Departing Saturday, October 17, 2026

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    Thames Valley BusesNational Express2h 1m • 1 change

Frequently asked questions

Want to know about travelling from Slough to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Slough to Southampton.ExpandLaunch map view
  • Distance: 69.5 mi
  • Duration: 2h 26m

What companies run services between Slough, England and Southampton, England?

You can take a bus from Landmark Place to Coach Station via Heathrow Terminal 5 in around 2h 31m.

Operators