The average bus between Slough and Thame takes 1h 54m and the fastest bus takes 1h 45m. There is a bus service every few hours from Slough to Thame. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Slough and Thame. The earliest departure is at 6:08 AM in the morning, and the last departure from Slough is at 7:55 PM which arrives into Thame at 10:02 PM. All services require a transfer, and take on average 1h 54m. The schedules shown below are for the next available departures.

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1h 45m • 1 change

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Want to know about travelling from Slough to Thame? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Thame. However, there are services departing from Slough station and arriving at Thame station via High Wycombe BusStn. The journey, including transfers, takes approximately 1h 54m.
Slough to Thame bus services, operated by First Berkshire & The Thames Valley, depart from Wellington Street Stop F station.
Slough to Thame bus services, operated by First Berkshire & The Thames Valley, arrive at Town Hall station.
The distance between Slough and Thame is 37.5 km. The road distance is 53 km.
You can take a bus from Wellington Street Stop F to Town Hall via High Wycombe BusStn in around 2h 12m.