The average bus between South Boston and Chicago takes 25h 41m and the fastest bus takes 21h 10m. The bus service runs several times per day from South Boston to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between South Boston and Chicago. The earliest departure is at 12:55 AM at night, and the last departure from South Boston is at 5:15 PM which arrives into Chicago at 12:25 PM. All services require a transfer, and take on average 25h 41m. The schedules shown below are for the next available departures.
Want to know about travelling from South Boston to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from South Boston to Chicago. However, there are services departing from Boston station and arriving at Chicago Bus Station via Newark Penn Station. The journey, including transfers, takes approximately 25h 41m.
South Boston to Chicago bus services, operated by Greyhound USA, depart from Boston station.
South Boston to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Book your South Boston to Chicago bus tickets online with Omio and FlixBus.
The distance between South Boston and Chicago is 1366.4 km. The road distance is 1579 km.
You can take a bus from Boston to Chicago Bus Station via Newark Penn Station in around 26h.
