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South Portland to Manchester buses

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Trip Overview

The average bus between South Portland and Manchester takes 8h 16m and the fastest bus takes 5h 5m. The bus service runs several times per day from South Portland to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 16m
Duration
164 mi
Distance
$46
Average price
Twice daily
Frequency

South Portland to Manchester bus times

Buses run twice daily between South Portland and Manchester. The earliest departure is at 6:48 AM in the morning, and the last departure from South Portland is at 9:39 PM which arrives into Manchester at 8:10 AM. All services require a transfer at Congress St + Forest Ave and take an average of 8h 16m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA5h 5m • 3 changes
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    Arrives next day

    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA10h 30m • 3 changes

Departing Friday, November 13, 2026

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    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA5h 5m • 3 changes
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    Arrives next day

    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA10h 30m • 3 changes

Departing Sunday, November 15, 2026

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    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA7h 31m • 3 changes
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    Arrives next day

    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA15h 59m • 3 changes

Departing Monday, November 16, 2026

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    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA5h 5m • 3 changes
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    Arrives next day

    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA10h 30m • 3 changes

Departing Tuesday, November 17, 2026

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    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA5h 5m • 3 changes
  •  → 

    Arrives next day

    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA10h 30m • 3 changes

Departing Wednesday, November 18, 2026

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    Greater Portland Metro BusGreater Portland Metro BusAmtrak ThruwayGreyhound USA5h 5m • 3 changes

Frequently asked questions

Want to know about travelling from South Portland to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from South Portland to Manchester.ExpandLaunch map view
  • Distance: 164.3 mi
  • Duration: 8h 16m

What companies run services between South Portland, ME, USA and Manchester, NH, USA?

You can take a bus from Sawyer + Broadway to Manchester(Veterans Memorial Park) via Congress St + Forest Ave, Portland, ME, Boston, MA - South Station, and Boston in around 5h 14m.

Operators