The average bus between South San Francisco and American Canyon takes 4h 32m and the fastest bus takes 2h 24m. The bus service runs several times per day from South San Francisco to American Canyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between South San Francisco and American Canyon. The earliest departure is at 5:29 AM in the morning, and the last departure from South San Francisco is at 9:35 PM which arrives into American Canyon at 8:18 AM. All services require a transfer at Mission St & 1st St and take an average of 4h 32m. The schedules shown below are for the next available departures.


2h 29m • 2 changes


2h 24m • 2 changes
Arrives next day


9h 28m • 2 changes


2h 29m • 2 changes


2h 24m • 2 changes
Arrives next day


9h 28m • 2 changes


2h 29m • 2 changes


2h 24m • 2 changes
Arrives next day


9h 28m • 2 changes
Want to know about travelling from South San Francisco to American Canyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from South San Francisco to American Canyon. However, there are services departing from South San Francisco station and arriving at American Canyon station via Mission St & 1st St. The journey, including transfers, takes approximately 4h 32m.
South San Francisco to American Canyon bus services, operated by SamTrans, depart from Airport Blvd & Baden Ave station.
South San Francisco to American Canyon bus services, operated by SamTrans, arrive at Rio del Mar at Carolyn Dr station.
The distance between South San Francisco and American Canyon is 59.3 km. The road distance is 81 km.
You can take a bus from Airport Blvd & Baden Ave to Rio del Mar at Carolyn Dr via Mission St & 1st St, San Francisco Ferry Building, Vallejo Transit Center, and Vallejo Ferry Terminal in around 4h 9m.