The average bus between South Station and Osterville takes 3h 50m and the fastest bus takes 2h 20m. The bus service runs several times per day from South Station to Osterville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between South Station and Osterville. The earliest departure is at 8:00 AM in the morning, and the last departure from South Station is at 8:00 PM which arrives into Osterville at 7:50 AM. All services require a transfer, and take on average 3h 50m. The schedules shown below are for the next available departures.

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Want to know about travelling from South Station to Osterville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from South Station to Osterville. However, there are services departing from South Station station and arriving at Osterville station via Hyannis Transportation Center. The journey, including transfers, takes approximately 3h 50m.
South Station to Osterville bus services, operated by Peter Pan Bus Lines, depart from Boston South Station.
South Station to Osterville bus services, operated by Peter Pan Bus Lines, arrive at Hyannis Transportation Center station.
The distance between South Station and Osterville is 97.5 km. The road distance is 127 km.
Peter Pan Bus Lines operates a bus from Boston South Station to Hyannis Transportation Center every 3 hours. Tickets cost $15–40 and the journey takes 1h 35m.