The average bus between Southampton and Cheadle takes 8h 3m and the fastest bus takes 6h 29m. The bus service runs several times per day from Southampton to Cheadle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Southampton and Cheadle. The earliest departure is at 4:15 AM at night, and the last departure from Southampton is at 8:30 PM which arrives into Cheadle at 8:14 AM. All services require a transfer at London Heathrow Airport and take an average of 8h 3m. The schedules shown below are for the next available departures.


6h 49m • 2 changes


6h 29m • 2 changes
Arrives next day


10h 39m • 2 changes


6h 29m • 2 changes


7h 39m • 2 changes


6h 29m • 2 changes
Arrives next day


10h 39m • 2 changes


6h 29m • 2 changes


7h 39m • 2 changes


6h 29m • 2 changes
Arrives next day


10h 39m • 2 changes


6h 29m • 2 changes


7h 39m • 2 changes


6h 29m • 2 changes
Arrives next day


10h 39m • 2 changes
Want to know about travelling from Southampton to Cheadle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Cheadle. However, there are services departing from Southampton station and arriving at Cheadle station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 8h 3m.
Southampton to Cheadle bus services, operated by National Express, depart from Coach Station.
Southampton to Cheadle bus services, operated by National Express, arrive at Stoke-on-Trent station.
The distance between Southampton and Cheadle is 235.3 km. The road distance is 379 km.
You can take a bus from Coach Station to Cross Street via London Heathrow Airport and bus station in around 7h 9m.