The average bus between Southampton and Duston takes 6h 19m and the fastest bus takes 4h 26m. The bus service runs several times per day from Southampton to Duston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Southampton and Duston. The earliest departure is at 5:15 AM in the morning, and the last departure from Southampton is at 1:45 PM which arrives into Duston at 6:32 PM. All services require a transfer at London Heathrow Airport and take an average of 6h 19m. The schedules shown below are for the next available departures.



5h 6m • 3 changes


4h 56m • 3 changes


4h 26m • 3 changes


5h 4m • 3 changesWant to know about travelling from Southampton to Duston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Duston. However, there are services departing from Southampton station and arriving at Duston station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 6h 19m.
Southampton to Duston bus services, operated by National Express, depart from Coach Station.
Southampton to Duston bus services, operated by National Express, arrive at Northampton station.
The distance between Southampton and Duston is 152.6 km. The road distance is 224 km.
You can take a bus from Coach Station to Duston Road via London Heathrow Airport, Lake, and Northampton Bus Interchange in around 5h 25m.