Bus Southampton to Great Portland Street (Station) from £46 | Tickets & Timetables

Southampton to Great Portland Street (Station) buses

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Trip Overview

The average bus between Southampton and Great Portland Street (Station) takes 3h 25m and the fastest bus takes 3h 1m. The bus service runs several times per day from Southampton to Great Portland Street (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 25m
Duration: 81 mi
Distance: £46
Average price: 5 times a day
Frequency

Bus

best

Take the bus from Coach Station to Heathrow Terminal 5bus 032

2h 15m

£25–71

Southampton to Great Portland Street (Station) bus times

Buses run 5 times a day between Southampton and Great Portland Street (Station). The earliest departure is at 4:05 AM at night, and the last departure from Southampton is at 4:45 PM which arrives into Great Portland Street (Station) at 8:07 PM. All services require a transfer at Heathrow Terminal 5 and take an average of 3h 25m. The schedules shown below are for the next available departures.

Departing Friday, August 21, 2026

4:05 AM → 7:11 AM
3h 6m • 1 change
6:05 AM → 9:38 AM
3h 33m • 1 change
10:45 AM → 2:15 PM
3h 30m • 1 change
2:45 PM → 6:15 PM
3h 30m • 1 change
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Departing Saturday, August 22, 2026

4:05 AM → 7:06 AM
3h 1m • 1 change
6:05 AM → 9:34 AM
3h 29m • 1 change
10:45 AM → 2:14 PM
3h 29m • 1 change
2:45 PM → 6:15 PM
3h 30m • 1 change
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Departing Sunday, August 23, 2026

4:05 AM → 7:08 AM
3h 3m • 1 change
6:05 AM → 9:30 AM
3h 25m • 1 change
10:45 AM → 2:23 PM
3h 38m • 1 change
2:45 PM → 6:21 PM
3h 36m • 1 change
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Departing Monday, August 24, 2026

4:05 AM → 7:12 AM
3h 7m • 1 change
6:05 AM → 9:41 AM
3h 36m • 1 change
10:45 AM → 2:15 PM
3h 30m • 1 change
2:45 PM → 6:14 PM
3h 29m • 1 change
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Departing Tuesday, August 25, 2026

4:05 AM → 7:12 AM
3h 7m • 1 change
6:05 AM → 9:41 AM
3h 36m • 1 change
10:45 AM → 2:15 PM
3h 30m • 1 change
2:45 PM → 6:14 PM
3h 29m • 1 change
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Departing Wednesday, August 26, 2026

4:05 AM → 7:12 AM
3h 7m • 1 change
6:05 AM → 9:41 AM
3h 36m • 1 change
10:45 AM → 2:15 PM
3h 30m • 1 change
2:45 PM → 6:14 PM
3h 29m • 1 change
Show more

Departing Thursday, August 27, 2026

4:05 AM → 7:12 AM
3h 7m • 1 change
6:05 AM → 9:41 AM
3h 36m • 1 change
10:45 AM → 2:15 PM
3h 30m • 1 change
2:45 PM → 6:14 PM
3h 29m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Southampton to Great Portland Street (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.