The average bus between Southampton and Harpenden takes 4h 43m and the fastest bus takes 3h 48m. The bus service runs several times per day from Southampton to Harpenden. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Southampton and Harpenden. The earliest departure is at 4:05 AM at night, and the last departure from Southampton is at 9:25 PM which arrives into Harpenden at 5:01 AM. All services require a transfer at Heathrow Central Bus Station and take an average of 4h 43m. The schedules shown below are for the next available departures.


4h 25m • 2 changes

4h 25m • 2 changes

4h 17m • 2 changes

4h 21m • 2 changes

3h 48m • 2 changes

3h 57m • 2 changes

3h 58m • 2 changes

4h 26m • 2 changes

3h 49m • 2 changes

4h 9m • 2 changes

4h 9m • 2 changes

4h 39m • 2 changes

5h 19m • 2 changes

4h 35m • 2 changes

4h 10m • 2 changes

3h 55m • 2 changes

5h 19m • 2 changes

4h 35m • 2 changes

4h 10m • 2 changes

3h 55m • 2 changesWant to know about travelling from Southampton to Harpenden? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Harpenden. However, there are services departing from Southampton station and arriving at Harpenden station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 4h 43m.
Southampton to Harpenden bus services, operated by National Express, depart from Coach Station.
Southampton to Harpenden bus services, operated by National Express, arrive at Luton Station Interchange.
The distance between Southampton and Harpenden is 124.9 km. The road distance is 180 km.
You can take a bus from Coach Station to Old Cock Inn via Heathrow Central Bus Station and Luton Station Interchange in around 4h 17m.